Meet Ingrid Luyten

Ingrid Luyten obtained a Master’s degree in Chemistry and a Ph.D. degree in Organic Chemistry at the University of Leuven (Belgium). She is a European Patent Attorney and holds a “Queen Mary” degree, which is the equivalent to the CEIPI. She has been working in the field of Intellectual Property for over 10 years and is in charge of patent and litigation cases particularly relating to the pharmaceutical industry and agricultural sciences. Before working at Gevers, Ingrid worked at SOLVAY for 13 years and held positions as a senior research specialist and analyst and in legal IP affairs. Through her experience at SOLVAY and her actual position as an IP Counsel at Gevers, Ingrid has worked on the protection of several kinds of inventions in the field of chemistry. She has experience in industrial small organic chemicals, such as heterocyclic compounds and macromolecular chemicals, such as polymers, nucleic acids and peptides, their synthesis and structural characteristics (inorganic chemistry). She advises and represents you on patentability of inventions, IP protection strategies, patent infringement and enforcement, patent validity and technology. She defends cases in patent prosecution, opposition proceedings, patent infringement and nullity actions. She handles cases in English and Dutch and is sufficiently proficient in French and German to handle texts written in those languages. She also advises French-speaking inventors. Currently, she is very active in training young PhD technologists to become proficient patent attorneys.

• 1989-1994 : PhD in Heterocyclic Chemistry – Katholieke Universiteit Leuven
• 1.2.1994 -30.9.1995: Postdoctoraal researcher – Laboratorium voor Medicinale Scheikunde, Katholieke Universiteit Leuven Belgium – Synthesis of modified nucleic acids.
• 1.10.1995 -31.03.1996: Postdoctoral researcher – Bijvoet Center voor Biomoleculair Onderzoek, Netherlands, Biomolecular NMR on proteins
• 1.04.1996 – 30.09.1997 : Postdoctoral researcher – Department of Bioorganic Chemistry, University of Uppsala, Sweden, NMR on nucleosides
• 30.09.1997- 28.02.2001 : FWO fellowship Postdoctoral researcher, Chemistry / Pharmaceutical department – Katholieke Universiteit Leuven, NMR Structural determination of RNA, DNA and RNA/protein complexes – collaboration with EMBL in Germany.

• European Patent Attorney

• 31 scientific publications and 1 review article (Hybridization properties of base modified oligonucleotides within the double- and triple-helix motif. I. Luyten, P. Herdewijn, Eur. J. Med. Chem. (0.809), 33, 1998, 515. )
• Relevant articles out of the list of 31 scientific publications
• 5. 2’-Deoxyuridines with a 5-heteroaromatic substituent: synthesis and biological evaluation. I. Luyten, L. Jie, A. Van Aerschot, C. Pannecouque, P. Wigerinck, J. Rozenski, C. Hendrix, C. Wang, L. Wiebe, J. Balzarini, E. De Clerq and P. Herdewijn, Antiviral Chem. Chemotherapy (1.607), 6, 1995, 262.
• 17. Solution Structure of a 9-(2-O-D-Ribofuranosyl)-D-ribofuranosyladenine-substituted RNA Decamer Duplex. I. Luyten, R. M. Esnouf, S. N. Mikhailov, P. Michiels, H. A. Heus, C. W. Hilbers and P. Herdewijn, Helv. Chim. Acta (2.683), 83, 2000, 1278.
• 18. Cyclohexene nucleic acid (CeNA): a nuclease stable oligonucleotide that activates RNase H and increases duplex stability with complementary RNA. J. Wang, B. Verbeure, I. Luyten, E. Lescrinier, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot, P. Herdewijn, J. Am. Chem. Soc. (5.650), 122, 2000, 8595
• 22, Cyclohexene nucleic acids (CeNA) form stable duplexes with RNA and induce RNase H activity. Wang J., Verbeure B., Luyten I., Froeyen M., Hendrix C,. Rosemeyer H., Seela F., Van Aerschot A. and Herdewijn P Nucleosides, Nucleotides & Nucleic Acids. 20(4-7) 2001, 785-788.
• 27. Structural basis for recognition of the intron branch site RNA by splicing factor 1. Liu ZH., Luyten I., Bottomley MJ., Messias AC., Houngninou-Molango S., Sprangers R., Zanier K., Kramer A., Sattler M. Science. 294(5544), 2001, 1098-1102. (first two authors contributed equally to the work).
• 28. Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression of the intron branch site RNA by splicing factor 1. Zanier K., Luyten I., Crombie C., Muller B., Schumperli D., Linge JP., Nilges M., Sattler M.; Rna-A Publication of the Rna Society. 8(1), 2002, 29-46.
• 29. Guest Encapsulation and Self-Assembly of Molecular Capsules in Polar Solvents via Multiple Ionic Interactions.
• Francesca Corbellini, Roberto Fiammengo, Peter Timmerman, Kees Versluis, Albert J. R. Heck, Ingrid Luyten, and David N. Reinhoudt, J. of the Am. Chem. Soc. 124(23), 2002, 6569-6575.